This test detects antibodies specific to Treponema pallidum, the bacterium that causes syphilis. Unlike the screening VDRL test, this treponemal test is more specific and is typically used to confirm a reactive VDRL result.
Why is the Syphilis TP done?
Ordered to confirm a reactive VDRL screening result, or sometimes as a primary test, since it remains positive even after successful treatment (unlike VDRL, which typically becomes non-reactive).
It can help your doctor assess
Confirms current or past syphilis infection.
Who may need this test?
This test may be considered for:
Anyone with a reactive VDRL result needing confirmation
Those with symptoms or exposure suggestive of syphilis.
Whether this test is right for you depends on your symptoms, medical history and the reason for testing - your doctor can advise.
What does this test measure?
Specific antibodies against Treponema pallidum, the bacterium responsible for syphilis.
Treponema Pallidum Antibody
Syphilis Confirmation
More specific than VDRL for confirming true syphilis infection, though it typically stays positive for life even after successful treatment - so it can’t distinguish active from past-treated infection on its own.
Understanding your Syphilis TP results
How to read your result
Your report should be read using the reference interval, unit and method shown by the performing laboratory. A result outside a reference interval does not automatically establish a diagnosis, and a result inside the interval does not rule out every health problem. Clinical interpretation depends on symptoms, history and other findings.
Marker
Result
What it may be associated with
TP Antibody
Reactive/Positive
Confirms current or past syphilis infection - your doctor will use your treatment history and VDRL titre to determine if active treatment is needed.
If a result is outside the range
If the Syphilis TP is reported as high, low, positive, negative or otherwise outside the laboratory's stated interval, the meaning depends on the specific test and the reason it was ordered. Your clinician may consider repeat testing, related investigations or other clinical information before deciding what the result means.
Limitations of this test
Because it stays positive long-term, this test confirms exposure but not necessarily current disease activity - VDRL titres are used to monitor treatment response instead.
An abnormal result does not by itself mean you have a particular disease. Your doctor interprets results together with your symptoms, history and other tests.
Syphilis TP normal range
Parameter
Reference range
Unit
TP Antibody
Non-reactive (negative)
—
Typical adult ranges for guidance. Reference intervals vary with the laboratory method, age and sex - always read your result against the range printed on your own report.
How should I prepare for the Syphilis TP?
No fasting is needed - you can eat and drink normally.
Drink water as usual - being well hydrated makes the blood draw easier.
Tell the collection team about any medicines and supplements you take.
Do not stop prescribed medicines unless your doctor tells you to.
Follow any additional instructions our team shares when you book.
How sample collection works
01
Book
Choose the test and a time slot online, or call us and we'll book it for you.
02
Prepare
Follow the preparation steps above for this test.
03
Sample collection
A trained phlebotomist collects the sample at your home - no extra charge.
04
Laboratory processing
Your sample is processed in our laboratory and reviewed by a pathologist.
05
Report
Your report is shared on WhatsApp and email, usually within 24 hours.
For a blood-based test, a small blood sample is collected by a trained healthcare professional, usually from a vein in the arm. The collection normally takes only a few minutes; mild temporary discomfort or bruising can occur at the puncture site.
What can affect the result?
This test typically remains positive for life after true infection, even following successful treatment, so it can’t be used alone to judge treatment response.
When should you talk to a doctor?
Laboratory results are interpreted together with your symptoms, medical history and other investigations. If your results are significantly abnormal, or you have symptoms that worry you, discuss them with a qualified doctor promptly.
Test details
Test name
Syphilis TP
Test code
HWP-T0179
Department
Clinical Biochemistry
Sample type
Venous blood (from a vein in the arm)
Fasting
Not required
Report time
24 hours (next day)
Home collection
Available across Malad, Kandivali, Borivali & Goregaon
Price
₹1,699 (MRP ₹2,249, 24% off)
Availability
All days - lab open 24×7
References
Trusted public health sources for the information on this page:
1.Syphilis Tests - MedlinePlus (US National Library of Medicine)
This information is for general awareness and does not replace advice from your doctor.
₹1,699₹2,24924% off
Syphilis TP test price in Mumbai
The Syphilis TP test cost in Mumbai at HWP Diagnostic is ₹1,699 - 24% less than the MRP of ₹2,249. There are no extra charges for home sample collection. The same price applies across Malad, Kandivali, Borivali and Goregaon.
Book the Syphilis TP test with free home sample collection anywhere in Malad, Kandivali, Borivali and Goregaon, or walk in to our lab in Malad West, Mumbai - open 24×7.
VDRL can occasionally give false positives, so this more specific treponemal test confirms whether a reactive VDRL truly reflects syphilis infection.
Will this test stay positive even after treatment?
Yes, in most people it remains positive for life once infected, even after successful treatment - so your doctor uses VDRL titre trends, not this test, to monitor treatment success.
What is the Syphilis TP?
Syphilis TP is a blood test. Syphilis TP looks for evidence of infection - antigen, antibody or genetic material - to help confirm the cause of symptoms and guide treatment.
Why is the Syphilis TP done?
The Syphilis TP may be ordered when a healthcare professional needs information about the condition or health area assessed by this test. Syphilis TP looks for evidence of infection - antigen, antibody or genetic material - to help confirm the cause of symptoms and guide treatment. At HWP Diagnostic the sample can be collected free at your home in Malad and nearby Mumbai areas, and the report is usually shared within the same day or next day. Please carry or upload your doctor's prescription where the test needs one, and discuss the result with your doctor for a full interpretation.
What does the Syphilis TP test measure?
Syphilis TP looks for evidence of infection - antigen, antibody or genetic material - to help confirm the cause of symptoms and guide treatment.
Who may need the Syphilis TP?
The test may be relevant for people whose symptoms, medical history, screening needs or treatment monitoring match the purpose of the Syphilis TP.
How should I prepare for the Syphilis TP?
No special preparation is needed for this test.
Do I need to fast for the Syphilis TP?
No, fasting is not required for the Syphilis TP. You can eat and drink normally unless your doctor has advised otherwise.
What sample is required for the Syphilis TP?
The Syphilis TP is done on a blood sample.
How is the Syphilis TP sample collected?
For a blood-based test, a small blood sample is collected by a trained healthcare professional, usually from a vein in the arm. The collection normally takes only a few minutes; mild temporary discomfort or bruising can occur at the puncture site.
How long does the Syphilis TP take to report?
Reports for the Syphilis TP are usually ready within 24 hours of sample collection. You receive them on WhatsApp and email.
What is the price of the Syphilis TP?
The Syphilis TP costs Rs 1050 at HWP Diagnostic (MRP Rs 1400). Home sample collection is free.
How do I understand my Syphilis TP result?
Your report should be read using the reference interval, unit and method shown by the performing laboratory. A result outside a reference interval does not automatically establish a diagnosis, and a result inside the interval does not rule out every health problem. Clinical interpretation depends on symptoms, history and other findings.
What does a high or low Syphilis TP result mean?
If the Syphilis TP is reported as high, low, positive, negative or otherwise outside the laboratory's stated interval, the meaning depends on the specific test and the reason it was ordered. Your clinician may consider repeat testing, related investigations or other clinical information before deciding what the result means.
Can a Syphilis TP diagnose a disease by itself?
The Syphilis TP can provide important information, but laboratory results are generally interpreted together with symptoms, medical history, examination and other investigations. A single result should not be treated as a diagnosis without clinical context.
Can medicines affect the Syphilis TP result?
Some medicines, supplements, food, exercise and other pre-test factors can affect particular laboratory results. Tell the healthcare professional about medicines and supplements you take, and do not stop prescribed medicines unless your clinician tells you to.
Is the Syphilis TP available for home collection?
Yes. Free home sample collection for the Syphilis TP is available across Malad, Kandivali, Borivali and Goregaon in Mumbai. You can also visit our Malad West lab, open 24x7.
What is the Syphilis TP test?Why is the Syphilis TP test done?